Tıbbi Biyoloji ve Genetik (DR)
Ders İçerikleri
1. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| LEE6500 | Scientific Research Methods and Ethics | 3+0+ | 9 | Compulsory |
| The nature and development process of scientific knowledge, methods and methodological principles in social sciences, some basic concepts related to scientific research methods, quantitative and qualitative data collection and analysis techniques, ethical rules to be applied in scientific research and citation formats and techniques in accordance with ethical rules. | ||||
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6113 | Advanced Cell Biology and the Genome | 3+0+ | 11 | Compulsory |
| As a result of the genome and molecular structure course, students gain knowledge about the structure and functions of the genome after receiving basic information about the cell. | ||||
3. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6171 | Seminar | 0+0+0 | 30 | Compulsory |
| It includes scientific presentations prepared by the student. | ||||
4. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6172 | Qualifying examination | 0+0+ | 30 | Compulsory |
5. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6115 | Thesis Study I | 0+0+ | 30 | Compulsory |
| Thesis study | ||||
6. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6116 | Thesis Study II | 0+0+ | 30 | Compulsory |
| Thesis study | ||||
7. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6117 | Thesis Study III | 0+0+ | 30 | Compulsory |
| Tez çalışması | ||||
8. Semester
| Course Code | Course Name | (T+A+L) | ECTS | Compulsory/Elective |
| TGY6118 | Thesis Study IV | 0+0+ | 30 | Compulsory |
| Thesis study | ||||
Department/Programme Elective Courses
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6001 | Cytogenetics and Molecular Genetics Techniques and Application Areas | 3+0+0 | 8 |
| The aim of this course is to provide information about cancer cytogenetics and its clinical relevance. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6002 | Personalized Treatment | 3+0+0 | 8 |
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6008 | Non-coding Regions in the Genome | 3+0+0 | 8 |
| The students will be taught basic information about DNA regions that do not have code. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6009 | Cancer Genetics | 3+0+ | 8 |
| Molecular and genetic mechanisms in cancer. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6011 | Biostatistics | 3+0+ | 8 |
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6013 | Epigenetics | 3+0+0 | 8 |
| Epigenetics: The New Science of Genetics, Mechanisms of DNA Methylation, Mechanisms of Histone Modifications, The Epigenetics of Non-coding RNA, Analysis of Gene-specific DNA Methylation/ Methods for Assessing Genome-wide DNA Methylation, DNA Hypomethylation in Cancer, Altered Histone Modifications in Cancer, Gene Regulation During Tumorigenesis, Epigenetic Regulation of miRNAs in Cancer, Epigenetic Regulation of miRNAs in Cancer, Epigenetic Changes During Cell Transformation, Epigenetic Reprogramming of Mesenchymal Stem Cells, Epigenetic Targeting Therapies to Overcome | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6014 | Molecular Techniques and Application Areas | 3+0+0 | 8 |
| USE OF PHENOL CHLOROFORM METHOD IN DNA ISOLATION, USE OF SPIN COLUMN METHOD IN DNA ISOLATION, USE OF MAGNETIC BEADS IN DNA ISOLATION, PCR AND MOST USED PCR TYPES, AGAROSE GEL ELECTROPHORESIS METHOD, SANGER SEQUENCE METHOD AND ITS AREAS OF USE, RFLP METHOD AND ITS USE AREAS, RNA TRACE PHENOL CHLOROFORM AND USE OF SPIN COLUMN METHOD, CDNA SYNTHESIS AND REAL TIME PCR TECHNIQUES AND AREAS OF USE, USE OF ACGH AND MLPA TECHNIQUES IN GENETIC DIAGNOSIS, NEW GENERATION SEQUENCING METHODS AND COMPARISON OF ALL SEQUENCING METHODS, METHODS USED IN MIRNA ISOLATION | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6017 | Molecular Immunology | 3+0+0 | 8 |
| Moleküler İmmünoloji dersi sonucu öğrenciler immünoloji ile ilgili temel bilgiler aldıktan sonra, immün sistem ve fonksiyonları hakkında bilgi sahibi olurlar. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6018 | Tumor Heterogeneity and Drug Resistance | 3+0+0 | 8 |
| Molecular and genetic mechanisms of tumoral heterogeneity observed in cancer and the parallel development of cancer drug resistance. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6102 | Tissue and Cell Culture | 3+0+0 | 8 |
| CELL CULTURE LAB. AND EQUIPMENTS, CELL CULTURE SAFETY RULES, PERIPHERAL BLOOD CELL CULTURE, BONE MARROW CELL CULTURE, AMNION CELL CULTURE, CVS CELL CULTURE, ABORT CELL CULTURE, 3D CELL CULTURE, STEM CELL CULTURE, PRIMARY CELL CULTURE, CANCER STEM CELL CULTURE, EX VIVO TISSUE CULTURE, EXPERIMENTAL ANIMAL MODELS | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6104 | Molecular Basis of Diseases | 2+0+0 | 8 |
| In this course, students acquire basic knowledge about the molecular pathogenesis of diseases. | |||
| Course Code | Course Name | (T+A+L) | ECTS |
| TGY6107 | Mutation and Mutation Screening Methods | 2+0+0 | 8 |
| Changes in chromosome structure and number, mutagenic effect of these changes (chromosome mutations). What is a gene mutation? Examining the molecular level of gene mutations, types, causes. Spontaneous mutations; Errors that occur during the replication of DNA, spontaneous chemical changes. What is a mutagen? Mutagen types; physical mutagens, types of ionizing radiation and chemical mutagens. Types of damage caused by mutagens in the DNA molecule. DNA repair mechanisms. Different mutation detection methods. | |||